Symptoms of Epididymitis
Epididymitis refers to inflammation of the epididymis that occurs when the body’s immune defenses are compromised, allowing pathogenic bacteria—such as Escherichia coli, Staphylococcus, and Streptococcus—to enter the vas deferens and ascend retrogradely into the epididymis. It predominantly affects young and middle-aged men. Clinically, epididymitis is generally categorized into two types: acute and chronic.
① Symptoms of Acute Epididymitis
In most cases, patients with acute epididymitis experience sudden onset of high fever, accompanied by elevated white blood cell counts on routine blood tests. The affected side of the scrotum becomes swollen and painful; the epididymis enlarges and feels heavy or dragging, with marked tenderness upon palpation. Referred pain may also occur in the lower abdomen and inguinal region. When inflammation spreads extensively, both the epididymis and testicle become swollen, and their anatomical boundaries become indistinct on physical examination—a condition termed epididymo-orchitis.

② Symptoms of Chronic Epididymitis
Scrotal pain is the hallmark symptom of chronic epididymitis, typically presenting as persistent or intermittent pain on the affected side. The pain is usually dull and accompanied by a sensation of fullness or heaviness. This discomfort may radiate to the lower abdomen and ipsilateral inguinal region, sometimes extending to the groin or upper thigh. Ipsilateral vas deferens thickening may also be observed. Notably, chronic epididymitis can lead to hydrocele; however, this manifestation is not universal and often occurs secondarily.