How is influenza screening performed?

Jul 28, 2022 Source: Cainiu Health
Dr. Guo Xiheng
Introduction
Influenza virus can cause acute respiratory symptoms and is highly contagious. Influenza screening is particularly important in clinical practice and can be performed through taking a detailed medical history, observing clinical symptoms, and conducting auxiliary examinations. Influenza virus infection may trigger viral myocarditis; therefore, if patients present with symptoms such as palpitations or chest tightness, timely diagnostic tests—including electrocardiography (ECG) and echocardiography—should be performed to confirm the diagnosis.

Influenza viruses belong to the family *Orthomyxoviridae* and are single-stranded, negative-sense, segmented RNA viruses. Based on differences in nucleoprotein (NP) and matrix protein (M), they are classified into four types: A, B, C, and D. Influenza viruses cause acute respiratory illness and are highly contagious. In clinical practice, influenza screening is particularly important and can be performed through the following steps:

I. History: Determine whether the patient had contact with individuals diagnosed with influenza prior to symptom onset.

II. Symptoms: Assess whether the patient exhibits influenza-like symptoms, such as high fever, headache, dizziness, cough, sore throat, and fatigue.

III. Diagnostic Tests:

1. Complete blood count (CBC): Influenza virus infection typically results in decreased total white blood cell (WBC) count and neutrophil percentage, along with an elevated lymphocyte percentage.

2. Etiological testing for influenza virus: Specific laboratory tests (e.g., rapid antigen detection, RT-PCR, or viral culture) can confirm influenza virus infection.

3. If pneumonia is suspected, chest X-ray or computed tomography (CT) may be performed to further evaluate disease severity and extent.