How long after taking dydrogesterone tablets will menstruation begin?

After taking dydrogesterone tablets, menstruation typically occurs 3–10 days after discontinuation. However, the exact timing may vary depending on individual differences. Below is a detailed analysis:

To induce menstruation, dydrogesterone tablets are usually taken continuously for approximately 10 days, followed by discontinuation. Upon stopping the medication, the sudden drop in progesterone levels triggers endometrial shedding, thereby initiating menstrual bleeding. If the endometrium is relatively thick, menstruation generally occurs within 3–7 days after discontinuing dydrogesterone.

If the endometrium is thin, it may take longer—approximately 10 days—for menstruation to occur; however, it rarely exceeds 10 days. Should spontaneous menstruation occur during dydrogesterone treatment, the medication should be discontinued immediately. If endometrial thickness is less than 8 mm, dydrogesterone alone is unlikely to successfully induce menstruation—and may even fail to do so. In such cases, other medications must first be administered to promote endometrial thickening, followed by combination therapy with dydrogesterone to achieve the desired menstrual induction effect.

Dydrogesterone is a progestogen medication that can help regulate menstrual cycles and induce menstruation. However, prolonged oral administration is not recommended, as it may lead to elevated progesterone levels or drug dependence. Prior to initiating dydrogesterone therapy, pelvic ultrasound is advised to assess endometrial thickness, and treatment should always be conducted under medical supervision.