What Causes Nipple Pain?
Nipple pain may occur under both physiological and pathological conditions. Common physiological causes include puberty-related pain, premenstrual pain, pregnancy-related pain, and postpartum or post-abortion pain. However, if nipple pain persists without relief—or even worsens—it may indicate an underlying pathological condition, warranting prompt medical evaluation and treatment. Below, we detail the possible causes of nipple pain.

What Causes Nipple Pain?
1. Physiological Causes
Nipple pain can arise from normal physiological processes. A common example is premenstrual breast tenderness, which results from elevated estrogen levels prior to menstruation. Estrogen stimulates breast tissue, leading to proliferative, tender swelling; once estrogen levels normalize after menstruation, the discomfort typically resolves. Other common physiological contributors include puberty, pregnancy, and the postpartum period.

2. Pathological Causes
(1) Breast Cancer
Breast cancer may cause nipple pain. The associated pain is typically persistent and progressively intensifies. It occurs unpredictably and lacks a consistent pattern. Additional signs often include palpable lumps in the nipple area, nipple asymmetry, darkening of the nipple or areola, and nipple retraction.
(2) Mammary Gland Hyperplasia (Benign Breast Disease)
Mammary gland hyperplasia may cause nipple pain, commonly presenting as dull or sharp, localized pain—often more pronounced on one side. Pain typically centers around palpable breast lumps and may radiate to the ipsilateral axilla or shoulder/back region. Some patients report itching or pain specifically at the nipple. Symptoms frequently appear or worsen several days before menstruation and subside or resolve after menstruation ends. Pain intensity may also fluctuate with emotional changes.

(3) Mastitis
Mastitis may cause nipple pain. Nipple tenderness is a hallmark symptom, worsening upon palpation or pressure. Concurrent nipple swelling is common. Breast pain is accompanied by localized tenderness; if left untreated, discomfort may progressively intensify—potentially evolving into pulsatile pain—and may be associated with erythema (redness) of the overlying skin.
The above outlines the main causes of nipple pain. We hope this information is helpful to you.