Why Does an Empty Gestational Sac Continue to Enlarge?
Many female patients feel relatively cheerful after becoming pregnant; however, some women develop a blighted ovum (also known as an “empty gestational sac”), which may continue to enlarge progressively. The underlying cause of this phenomenon remains unclear to many—why does the empty gestational sac keep growing?
Why Does an Empty Gestational Sac Continue to Enlarge?
The primary reason for continued growth of an empty gestational sac lies in the presence of trophoblastic cells within it. Human chorionic gonadotropin (hCG) is predominantly secreted by these trophoblastic cells. Even in the absence of an embryo, trophoblastic cells may persistently proliferate, differentiate, and secrete hCG—leading to continuously rising serum hCG levels. Therefore, ultrasound imaging—not hCG levels—is the principal diagnostic tool for identifying a blighted ovum. Ultrasound assessment focuses on the size of the gestational sac and the presence or absence of internal structures (e.g., yolk sac or embryo). Serum hCG values cannot reliably diagnose a blighted ovum, as they often remain elevated even in such cases.
A blighted ovum is closely associated with multiple factors, including chromosomal abnormalities, viral infections, medication exposure, environmental pollutants, and maternal systemic diseases. Illnesses, stress, emotional fluctuations, or home renovation during early pregnancy may also disrupt embryonic development and result in an empty gestational sac. Definitive diagnosis is typically confirmed via ultrasound examination around gestational week 8.
Once a blighted ovum is confirmed, prompt uterine evacuation (e.g., medical or surgical management) is required. Prior to conception, women are advised to undergo preconception genetic counseling and comprehensive pre-pregnancy health evaluations at a hospital, and to optimize their physical condition under physician guidance—thereby reducing the risk of blighted ovum occurrence. During recovery, dietary adjustments are essential: meals should be light and easily digestible, and adequate rest must be prioritized.We hope this information has been helpful to you!
