Medications for Treating Depression
Common medications for treating depression include fluoxetine hydrochloride capsules, paroxetine hydrochloride tablets, mirtazapine tablets, venlafaxine hydrochloride extended-release tablets, and bupropion hydrochloride extended-release tablets. Always follow your physician’s instructions when taking these medications.

1. Fluoxetine Hydrochloride Capsules
This medication is a selective serotonin reuptake inhibitor (SSRI). It alleviates depressive symptoms—such as low mood, diminished interest, and anxiety—by inhibiting the reuptake of serotonin at presynaptic neuronal membranes, thereby increasing synaptic serotonin concentration. It also improves sleep quality and appetite.
2. Paroxetine Hydrochloride Tablets
This drug selectively inhibits serotonin reuptake, elevating central serotonin levels and enhancing serotonergic neurotransmission. It helps regulate mood and reduce negative emotions—including depression, anxiety, and fear—and is particularly effective in patients with depression accompanied by significant anxiety symptoms.
3. Mirtazapine Tablets
Mirtazapine exerts its antidepressant effects primarily by enhancing central noradrenergic and serotonergic neurotransmission. It effectively improves sleep and appetite, while also alleviating anxiety and depressive symptoms, thereby enhancing emotional stability and overall quality of life.
4. Venlafaxine Hydrochloride Extended-Release Tablets
This medication is a serotonin–norepinephrine reuptake inhibitor (SNRI). By blocking the reuptake of both serotonin and norepinephrine, it increases their synaptic concentrations, producing robust antidepressant effects. It is especially effective in treating major depressive disorder and depression associated with prominent somatic symptoms.
5. Bupropion Hydrochloride Extended-Release Tablets
Bupropion primarily inhibits dopamine reuptake, thereby enhancing dopaminergic neurotransmission; it also exerts modest effects on norepinephrine and serotonin systems. It alleviates core depressive symptoms—including depressed mood and anhedonia—and offers mild stimulant and cognitive-enhancing effects. Notably, it is associated with a relatively lower risk of sexual side effects compared with other antidepressants.
Depression patients should use the above medications strictly under medical supervision and must not self-administer them arbitrarily. Maintain a light, balanced diet and avoid spicy or irritating foods—such as garlic, spicy hotpot, and mustard. Ensure adequate rest and avoid excessive physical or mental fatigue to safeguard overall health.