What causes missed periods for two months without pregnancy?

Aug 24, 2022 Source: Cainiu Health
Dr. Chen Zhe
Introduction
Missing your period for two months without pregnancy is most likely due to endocrine dysfunction. It is recommended that you discontinue restrictive dieting and weight-loss efforts and instead increase your nutritional intake; menstruation may then gradually resume. Alternatively, recent gynecological procedures—such as intrauterine device (IUD) insertion or uterine cavity surgery—may have caused cervical or intrauterine adhesions, leading to amenorrhea and hematometra (blood accumulation in the uterine cavity). On average, women menstruate every 28 days, with each period lasting 5–7 days.

Conditions that can cause menstrual irregularities include polycystic ovary syndrome (PCOS), pituitary microadenoma-induced hyperprolactinemia, endometrial polyps, endometritis, and myometritis. To rule out other underlying disorders, it is necessary to test the six key female sex hormones, five thyroid function parameters, and adrenal glucocorticoid levels—abnormalities in any of these may contribute to menstrual disturbances. So, what could be the cause if menstruation is absent for two months and pregnancy has been ruled out?

What causes amenorrhea for two months when pregnancy is excluded?

Amenorrhea lasting two months without pregnancy is most commonly attributable to endocrine imbalance. It is advisable to discontinue restrictive dieting or weight-loss efforts and instead improve nutritional intake; menstruation may then resume gradually. Alternatively, recent gynecological procedures—such as intrauterine device (IUD) insertion or uterine cavity surgery—may have led to cervical or intrauterine adhesions, resulting in amenorrhea and intrauterine blood accumulation. In general, women experience menstruation approximately every 28 days, with each period lasting 5–7 days. If a woman previously had regular cycles and experiences only an occasional two-month absence of menses, pregnancy should first be excluded through clinical evaluation.

In such cases, hormonal testing—including measurement of the six key reproductive hormones—is recommended. Results often reveal significantly low progesterone levels. Additionally, some patients may be diagnosed with PCOS, characterized by failure of ovarian follicles to mature and ovulate. In PCOS, luteinizing hormone (LH) levels are markedly elevated relative to follicle-stimulating hormone (FSH), and testosterone levels are also increased—both factors contributing to prolonged amenorrhea.

In daily life, maintain a regular, balanced diet; avoid spicy, stimulating foods, binge eating, and chronic sleep deprivation. We hope this information is helpful to you.