Optimal Treatment for Cerebral Lacunar Infarction

Aug 24, 2022 Source: Cainiu Health
Dr. Yang Jun
Introduction
The optimal treatment for lacunar infarction is the same as that for ischemic stroke. If the patient presents within 4.5 hours of symptom onset (i.e., during the acute phase), intravenous thrombolysis is indicated—currently one of the most effective treatments for ischemic stroke. Beyond this time window, antiplatelet agents such as aspirin or clopidogrel may be used. Generally, for lacunar infarction, dual antiplatelet therapy with aspirin plus clopidogrel may be administered for 21 days.

  The location of a cerebral infarction determines the type of sequelae. Infarcts in the anterior circulation more commonly result in hemiplegia, whereas those in the posterior circulation less frequently cause hemiplegia. Cerebral infarction is a severe cerebrovascular disease; thus, what is the optimal treatment for lacunar cerebral infarction?

  Optimal Treatment for Lacunar Cerebral Infarction

  The optimal treatment for lacunar cerebral infarction is essentially the same as for other types of cerebral infarction. If the patient presents within 4.5 hours of symptom onset (i.e., during the acute phase), intravenous thrombolysis is recommended—currently one of the most effective treatments for cerebral infarction. Beyond this therapeutic time window, antiplatelet agents such as aspirin or clopidogrel may be used. For lacunar cerebral infarction specifically, dual antiplatelet therapy with aspirin plus clopidogrel is typically administered for 21 days. Additionally, anti-atherosclerotic medications—particularly statins such as rosuvastatin and atorvastatin—should be initiated.

  For patients with cerebral infarction, aggressive secondary prevention is essential. Secondary prevention involves actively identifying and controlling risk factors. These include modifiable risk factors—such as hypertension, hyperglycemia, hyperlipidemia, and elevated homocysteine levels—as well as non-modifiable risk factors—including age and sex. Patients should rigorously control blood pressure and blood glucose levels. Those with diabetes must adhere strictly to a low-salt, low-fat, and diabetic-friendly diet.

  Patients with cerebral infarction must avoid smoking and alcohol consumption and limit intake of high-sodium foods. A light, low-salt diet is recommended to help prevent hemorrhage, hypertension, and hyperglycemia—thereby reducing the risk of recurrent cerebral infarction. We hope this information proves helpful to you.