Is nevus of Ota hereditary?
Sep 13, 2022
Source: Cainiu Health
Dr. Liu Wan
Introduction
Mongolian spots are generally not hereditary. They form due to a continuous increase in the number of melanocytes in the body, primarily caused by both congenital and acquired factors. The congenital factor involves impaired migration of melanocytes from the neural crest to the epidermis during embryonic development, causing melanocytes to become trapped in the dermal layer and resulting in the formation of brownish-gray pigmentation.
Acquired dermal melanocytosis is generally not hereditary. It forms due to a continuous increase in the number of melanocytes in the body, primarily influenced by both congenital and acquired factors, as detailed below:
1. Congenital factors: During embryonic development, the migration of melanocytes from the neural crest to the epidermis is obstructed, causing melanocytes to remain trapped in the dermal layer, thus forming acquired dermal melanocytosis.
2. Acquired factors: Long-term use of heavy metal-containing cosmetics, such as those with lead or mercury, may easily cause necrosis of skin fibrous tissues, leading to subcutaneous pigment deposition and the appearance of acquired dermal melanocytosis.
Acquired dermal melanocytosis can be removed through laser surgery. Based on the principle of selective photothermolysis, the laser targets pigment particles deposited in the dermal layer, effectively eliminating the pigmentation. It is important to maintain adequate rest, avoid staying up late, and ensure sufficient sleep. Diet should mainly consist of light and easily digestible foods; greasy or spicy irritants should be avoided as much as possible. Consume more fresh vegetables and fruits rich in vitamins, such as apples and pineapples.
