What causes skin keratinization?

Keratosis is a skin condition primarily characterized by excessive epidermal keratinization, resulting in localized hyperkeratosis, dry skin, scaling, and fissures. It usually causes no subjective discomfort, although occasional itching or pain may occur, often worsening during winter. So, what exactly is skin keratinization?

What Is Skin Keratinization?

Keratosis, also known as ichthyosis, is a group of skin disorders mainly defined by excessive epidermal keratinization. The condition primarily results from accelerated proliferation and keratinization of epidermal cells, while the shedding rate of dead skin cells does not keep pace, leading to keratin buildup. Abnormal desquamation means that normally produced keratin cannot be shed in time, potentially causing relative thickening of the stratum corneum. The cause is often associated with genetic factors in patients, although the exact cause remains unclear in some cases. Clinical manifestations may vary depending on the affected area and whether there is a familial pattern. Typically, involved skin areas develop keratin overgrowth, appearing rough, thickened, dry, and showing obvious flaking.

Skin roughness can result from deficiencies in vitamins A and B, which may stem from inadequate dietary intake, poor nutrition, or insufficient water consumption. Supplementing with adequate amounts of vitamins A and B can help restore smooth, fine skin. Excessive accumulation of keratin can restrict the skin, making it rough and dry, and preventing nutrients from skincare products from being properly absorbed. Regular exfoliation is essential to remove dead, aged skin cells. By eliminating this buildup, the skin can better absorb nutrients and moisture, overcoming roughness and dryness.

Phototherapy is a form of physical therapy widely adopted by dermatology departments in hospitals due to its high efficacy in treating keratotic skin conditions. Phototherapy not only serves as a primary treatment but also provides certain supportive benefits. Therefore, after undergoing phototherapy, patients with keratosis generally do not require additional adjunctive treatments. We hope this answer has been helpful to you. Wishing you good health and happiness.