Can I donate blood if my hepatitis B test shows positive for items 2, 4, and 5?
Sep 13, 2022
Source: Cainiu Health
Dr. Jin Zhongkui
Introduction
Individuals who test positive for hepatitis B markers 245 are not eligible to donate blood. If someone is found to be positive for hepatitis B 245, it generally does not indicate a significant health concern. For the general population, a positive result for hepatitis B 245 indicates prior exposure to the hepatitis B virus, possibly due to a latent infection. In the absence of clinical illness, the hepatitis B virus has typically been cleared from the body.
For the general population, a positive result for hepatitis B markers 245 indicates prior exposure to the hepatitis B virus, possibly due to a silent (asymptomatic) infection. In such cases, the body has likely cleared the virus without developing clinical illness. So, can someone with a positive HBV 245 test donate blood?
Can People with Positive Hepatitis B 245 Donate Blood?
Individuals who test positive for hepatitis B markers 245 are not allowed to donate blood. If someone is found to have a positive 245 result, it usually does not pose a significant health risk to themselves. For most people, a positive 245 indicates previous exposure to the hepatitis B virus, possibly through an asymptomatic infection. Without having developed symptoms, their bodies have largely eliminated the virus.A positive 245 simply means that the virus has left traces in the body after passing through—it confirms past infection.
When a person's health and immune system are functioning normally, the hepatitis B virus cannot easily become active, as the immune system effectively controls it. However, in rare extreme cases—such as individuals with cancer or malignant tumors—chemotherapy may be required. Chemotherapeutic agents can impair normal immune function, and in some instances, this may cause the previously suppressed hepatitis B virus (in those with 245 positivity) to reactivate, potentially shifting from 245 positive to 145 positive or even 135 positive.
At the same time, quantitative testing may show that the hepatitis B virus has turned positive again, indicating viral reactivation and replication. Therefore, from the standpoint of blood transfusion and donation safety, individuals with a positive 245 result are prohibited from donating blood to ensure maximum blood supply safety. We hope this answer has been helpful. Wishing you good health and happiness!
