What are the manifestations of occupational chronic severe benzene poisoning?

Chronic severe occupational benzene poisoning refers to a systemic disease caused by exposure to benzene or benzene-containing compounds during work, manifesting as mucocutaneous bleeding tendencies, nervous system damage, respiratory distress, hematopoietic system abnormalities, and central nervous system dysfunction.

1. Mucocutaneous bleeding tendency

Long-term inhalation of benzene-containing gases may lead to neutropenia and thrombocytopenia, resulting in a tendency for mucocutaneous bleeding, such as gum bleeding and irregular vaginal bleeding.

2. Nervous system damage

Benzene is an organic solvent that can enter the body through the skin, respiratory tract, and gastrointestinal tract. It is metabolized into harmful substances within the body, adversely affecting the nervous system and causing symptoms such as numbness in extremities, reduced touch sensation, and diminished pain perception.

3. Respiratory distress

Prolonged exposure to benzene-containing substances may result in benzene poisoning, affecting the central nervous system and leading to respiratory symptoms such as chest tightness, shortness of breath, and breathing difficulties.

4. Hematopoietic system abnormalities

Long-term or high-concentration exposure, particularly in cold environments, may suppress normal bone marrow function, reduce the number of hematopoietic cells in the bone marrow, and trigger conditions such as anemia, leukopenia, and thrombocytopenia.

5. Central nervous system abnormalities

Benzene may impair the normal functioning of the brain's central nervous system, leading to central nervous system damage that affects the patient's perception, cognition, motor coordination, and behavior.

After developing benzene poisoning, prompt medical attention is necessary. A comprehensive evaluation should be conducted to determine the specific health condition, and active treatment should be pursued under medical guidance to prevent symptom progression and increased treatment difficulty.