Can I take cephalosporin after drinking a sip of fruit wine?

Cephalosporins usually refer to cephalosporin antibiotics. In general, one should not take cephalosporin antibiotics after drinking a mouthful of fruit wine, as it may easily trigger a disulfiram-like reaction, causing significant discomfort in patients.

Fruit wine typically refers to alcoholic beverages made from various fruits such as grapes, waxberries, or plums. Although the ethanol content is relatively low, if cephalosporin antibiotics are taken, the ethanol present in the fruit wine can still interact with the medication and cause a disulfiram-like reaction. This may lead to symptoms such as laryngeal edema, difficulty breathing, and decreased blood pressure. In severe cases, it could result in anaphylactic shock, loss of consciousness, or even death. Therefore, cephalosporin antibiotics should not be taken after consuming even a small amount of fruit wine. Additionally, after consuming a mouthful of fruit wine, patients should also avoid taking other medications containing ingredients such as metronidazole or tolbutamide.

Besides fruit wine, patients who have consumed white liquor, beer, rice wine, or other alcoholic beverages generally should not take cephalosporin antibiotics either, as these medications must not be taken together with any food or medicine containing ethanol.