Does ASC-US with a negative HPV result mean cancer?
Jan 30, 2023
Source: Cainiu Health
Dr. Lv Aiming
Introduction
ASC-US generally belongs to atypical squamous cells of undetermined significance. It may result from abnormal vaginal discharge infected by bacteria, although human papillomavirus (HPV) has not been detected, possibly due to testing errors. When ASC-US is present but HPV test is negative, it usually does not have significant clinical implications and is often considered a result of inflammatory reactions in the body, which typically can resolve spontaneously.
ASC-US generally belongs to atypical squamous cells of undetermined significance, which may result from abnormal vaginal discharge and bacterial infection. Human papillomavirus (HPV) might not have been detected due to testing errors.
When ASC-US is present but HPV test results are negative, it usually has no significant clinical implication and is often considered a result of inflammatory response in the body. It is typically self-resolving and does not require specific treatment. However, patients should undergo regular follow-up examinations at the hospital to prevent potential complications and protect their health.
ASC-US is a result from cervical TCT (thinprep cytologic test), indicating atypical squamous cells whose significance is unclear. It is commonly found during initial cervical cancer screening. Abnormal cervical findings may stem from congenital or genetic factors and represent a form of cervical dysplasia. In severe cases, this condition could potentially lead to infertility. When such conditions are identified, colposcopy should be performed with biopsy; further management depends on the pathological results of the biopsy.
Patients should maintain a light diet, avoid spicy and irritating foods, engage in moderate physical exercise, and enhance immune function, all of which help promote recovery.
