What should I do if my nose keeps bleeding while taking targeted therapy drugs?

Nosebleeds during targeted therapy are commonly considered a side effect of the medication, although they may also be caused by other diseases. However, frequent nosebleeds while using targeted drugs are mostly attributed to drug-related side effects. Patients are advised to visit a hospital for a thorough evaluation and follow medical instructions carefully while closely monitoring their condition. In severe cases, hospitalization is strongly recommended.

As the name suggests, targeted drugs are a type of chemotherapy agent designed to act on specific molecular targets. Targeted therapy aims to deliver drugs or their carriers precisely to diseased tissues, where they accumulate or release active ingredients. Recurrent nosebleeds during targeted therapy may be related to drug side effects and should be evaluated through blood tests and coagulation function assessments. If test results are normal, the cause may instead be linked to nasal dryness or underlying nasal conditions.

If blood tests or coagulation function show abnormalities, the nosebleeds are likely due to side effects of the targeted therapy. Certain targeted drugs, such as apatinib mesylate and bevacizumab, are known to impair coagulation and platelet function, potentially leading to epistaxis (nosebleeds). Patients are advised to seek care at a reputable medical facility and undergo close monitoring. Hospitalization is recommended in particularly severe cases.