What is the serum aspartate aminotransferase value

Aspartate aminotransferase (AST), commonly known as serum glutamic-oxaloacetic transaminase (SGOT), is typically used to assess the extent of liver function damage.

SGOT is one of the clinical tests used in liver function evaluations and is normally distributed in tissues such as the myocardium, skeletal muscle, and liver. Elevated SGOT levels usually indicate liver damage, such as hepatocyte injury or liver inflammation. In such cases, medications like compound glycyrrhizin capsules or hepatoprotective tablets should be taken under medical guidance.

SGOT is primarily present within liver cells, and its measurement helps determine whether the liver has been injured. When cellular damage is severe, large amounts of SGOT are typically released into the bloodstream. Muscle disorders may also lead to increased SGOT levels, including conditions such as muscular atrophy and myositis, which require treatment with medications like idebenone tablets or vitamin B12 under a physician's supervision.

In addition, during acute myocardial infarction, not only SGOT but also serum creatine kinase-MB (CK-MB) levels are often elevated.