Is the Japanese encephalitis vaccine attenuated or inactivated?

Feb 24, 2023 Source: Cainiu Health
Dr. Jiang Weimin
Introduction
The Japanese encephalitis vaccine refers to the live attenuated vaccine for Japanese encephalitis. Under normal circumstances, the live vaccine for Japanese encephalitis is usually an attenuated vaccine rather than an inactivated one. Attenuated vaccines are an effective method for controlling Japanese encephalitis, capable of triggering the immune system to produce a sufficient immune response without causing the disease.

JE vaccine refers to the live vaccine for epidemic encephalitis B. Under normal circumstances, the live vaccine for epidemic encephalitis B is typically an attenuated vaccine rather than an inactivated vaccine. If any discomfort occurs, it is recommended to seek immediate medical treatment. The detailed explanation is as follows:

Attenuated vaccines are made from live viruses or live bacteria of pathogens that have undergone attenuation treatment. This means the pathogens have been modified so they no longer cause disease, yet they can still stimulate the immune system to produce a sufficient immune response, thereby providing protection against the original pathogen. Therefore, the live vaccine for epidemic encephalitis B uses an attenuated form of the epidemic encephalitis B virus, which does not cause epidemic encephalitis B, but effectively triggers the immune system to generate an immune response against the virus, thus offering protection.

Inactivated vaccines are made from pathogens that have been killed or inactivated, and therefore no longer have the ability to cause disease. Inactivated vaccines stimulate an immune response by introducing partial or complete components of the pathogen into the body.

Attenuated vaccines are an effective method for controlling epidemic encephalitis B, capable of triggering a robust immune response without causing the disease.