Is it a good thing if the interstitial tumor gene has not mutated?
Feb 25, 2023
Source: Cainiu Health
Dr. Peng Xiaodong
Introduction
Gastrointestinal stromal tumor (GIST) usually refers to a type of interstitial tumor. Generally, the absence of gene mutations in gastrointestinal stromal tumors is a favorable sign. It's important to maintain healthy eating habits and avoid spicy or irritating foods. Appropriate aerobic exercise can enhance the body's immunity. Adequate rest, maintaining a regular sleep schedule, balancing work and relaxation, and keeping a positive mood are also essential.
Gastrointestinal stromal tumors (GISTs) are commonly referred to as interstitial tumors. Generally, the absence of gene mutations in gastrointestinal stromal tumors is a positive sign.
About 80% of GIST cases are caused by mutations in two genes—C-KIT and PDGFRA—with C-KIT being the primary driver. Mutations in C-KIT promote cell proliferation and enhance cell survival. Therefore, in addition to endoscopic ultrasound examination, testing for C-KIT gene mutations significantly improves diagnostic accuracy for GISTs, achieving up to 90% when both methods are combined. The absence of gene mutations in gastrointestinal stromal tumors indicates that the C-KIT gene has not undergone mutation, suggesting the patient remains within a safe range. Hence, the lack of gene mutations in GISTs is a favorable outcome.
It is important to maintain healthy eating habits and avoid spicy or irritating foods. Regular aerobic exercise can boost immune function. Ensure adequate rest, maintain a regular sleep schedule, balance work and relaxation, and keep a positive mood. Additionally, if any discomfort occurs, seek medical evaluation promptly to prevent delays in diagnosis and treatment.
