How is CA125 tested?

Feb 28, 2023 Source: Cainiu Health

Dr. Qi Zhirong

Introduction

CA125 refers to carbohydrate antigen 125, which is generally tested through blood examination. Carbohydrate antigen 125 is a tumor marker used in cancer screening. In addition, elevated levels of carbohydrate antigen 125 may indicate endometriosis, which can be evaluated using abdominal and pelvic ultrasound or CT scans. Treatment should be tailored according to the underlying cause.

CA125 refers to carbohydrate antigen 125, which is generally tested through blood examination. Carbohydrate antigen 125 is a tumor marker used in cancer screening.

Carbohydrate antigen 125 is a laboratory indicator for pelvic tumors and is commonly associated with gynecological cancers such as cervical cancer and ovarian cancer. The test primarily involves a blood draw to determine whether the level of carbohydrate antigen 125 in the serum is elevated. The normal range for carbohydrate antigen 125 in serum is typically 0–35 U/mL. Elevated levels of carbohydrate antigen 125 suggest an abnormal condition in the body, which may be caused by benign diseases such as ovarian cysts. If the cyst is small, medications like Jinji Capsules or Guizhi Fuling Capsules may be used under a doctor's guidance. However, larger cysts may indicate malignant tumors such as ovarian cancer, which may require surgical treatment under medical supervision. After surgery, radiotherapy may be used as an adjunctive treatment.

In addition, elevated carbohydrate antigen 125 levels may also be associated with endometriosis, which can be evaluated using pelvic ultrasound or CT scans. Treatment should be tailored according to the underlying cause.

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What does the carbohydrate antigen CA125 test check for?

Carbohydrate antigen CA125 is primarily used to detect malignant tumors such as ovarian cancer, as well as benign conditions like uterine fibroids. Also known as cancer antigen 125, CA125 is a type of tumor marker. Elevated levels of this marker are commonly observed in various malignant tumors, including epithelial ovarian cancer, fallopian tube cancer, endometrial cancer, lung adenocarcinoma, and gastrointestinal adenocarcinomas.

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Is it necessary for healthy individuals to undergo CA125 testing?

CA125 testing is a tumor marker examination, and it is necessary for healthy individuals to undergo CA125 testing. The CA125 test requires a blood sample. It primarily reflects the metabolism and metastasis of solid malignant tumors. The normal range for CA125 is typically 0–35 U/ml, and under normal circumstances, CA125 levels in the blood are very low.

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Can the "three tumor markers" detect cancer?

The "three tumor markers" mainly refer to alpha-fetoprotein (AFP), carcinoembryonic antigen (CEA), and carbohydrate antigen CA125. Under normal circumstances, these three tumor markers can help detect tumors, although they may fail to identify early-stage tumors. When a tumor is present, the associated tumor markers usually increase. Therefore, if a patient's tumor marker levels are significantly higher than the normal range, it may indicate the presence of a tumor.

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Is a decrease in CA125 meaningful?

In general, a decrease in CA125 is meaningful. The specific analysis is as follows: CA125 is a commonly used tumor marker, primarily employed for screening and monitoring ovarian cancer. A decline in CA125 levels can reflect, to some extent, the effectiveness of treatment and tumor shrinkage, thus having certain clinical significance. A decreasing CA125 level is usually associated with effective treatment.

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Tumor Marker Antigen 125 U/ml

Cancer antigen 125 (CA125) U/ml is a protein normally produced by epithelial cells of the ovary. Under normal conditions, the concentration of CA125 is very low; however, in certain situations—such as the presence of malignant tumors like ovarian cancer—the level of CA125 can significantly increase.

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Is a CA125 value of 65.8 U/mL considered very high?

Under normal circumstances, a CA125 level of 65.8 U/mL is considered relatively high. CA125 is a common tumor marker used to detect gynecological malignancies such as ovarian cancer. Normally, the concentration of CA125 in the blood is low, typically less than 35 U/mL. When the CA125 concentration exceeds 35 U/mL,

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Is a CA125 level of 70 kU/L considered very high?

CA125 is a tumor marker commonly used to detect ovarian cancer in women. Normally, a CA125 level of 70 kU/L is considered quite high. The normal reference range for CA125 is generally 0–35 kU/L. Since a CA125 level of 70 kU/L far exceeds the normal range, it can be considered significantly elevated.

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What is the normal range for tumor markers in blood tests?

In general, the normal reference ranges for tumor markers in blood tests vary depending on the specific marker and laboratory standards, so exact values cannot be determined uniformly. Common tumor markers include carcinoembryonic antigen (CEA), carbohydrate antigen 125 (CA125), carbohydrate antigen 199 (CA199), and prostate-specific antigen (PSA). The defined normal ranges for each marker may differ among laboratories.

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