New nodules have reappeared after surgery for carcinoma in situ.

Mar 27, 2023 Source: Cainiu Health

Dr. Qi Zhirong

Introduction

New nodules appearing after surgery for carcinoma in situ may be due to incomplete resection during the operation, failure to follow medical instructions regarding medication, or inadequate daily care. It is important to seek timely medical attention to prevent worsening of the condition. Additionally, the recurrence could result from cancer cell metastasis prior to surgery. Patients should enhance postoperative care, avoid excessive fatigue, and attend regular follow-up appointments.

New nodules appearing after surgery for carcinoma in situ may be due to incomplete removal during surgery, failure to follow medical advice regarding medication, or inadequate daily care. Prompt medical attention is necessary to prevent worsening of the condition.

1. Incomplete surgical resection

If the lesion was not completely removed during surgery, residual tissue may remain and continue to grow, leading to the formation of new nodules. A comprehensive evaluation is required, followed by prompt performance of a second surgery to eliminate any remaining lesions, along with enhanced postoperative care.

2. Failure to follow medical advice regarding medication

Adjuvant chemotherapy drugs are needed after surgery to eliminate residual cancer cells. Not following the prescribed medication regimen may result in ineffective treatment and increase the risk of new nodule formation. A wedge resection may be recommended under medical guidance, followed by adjuvant chemotherapy using medications such as irinotecan hydrochloride for injection, pemetrexed disodium for injection, and cyclophosphamide for injection.

3. Inadequate daily care

Heavy smoking after surgery allows substances like nicotine and tar to enter the body, increasing the risk of cancer recurrence. For patients unable to tolerate surgery, molecular targeted therapies such as gefitinib, trametinib, or crizotinib may be used according to medical advice to promptly control disease progression.

In addition, new nodules may also result from pre-existing metastasis of cancer cells prior to surgery. Patients should strengthen postoperative care and avoid excessive fatigue.

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