What happens when liver function is abnormal in individuals with "big three positive" hepatitis?
Mar 28, 2023
Source: Cainiu Health
Dr. Jiang Weimin
Introduction
If liver function abnormalities in individuals with "big three positive" (chronic hepatitis B) are mild, there are generally no obvious functional impairments. In cases of mild liver damage, the liver's metabolic functions usually remain sufficient to prevent significant dysfunction. However, if the damage is more severe, it may lead to various liver function abnormalities, including disturbances in substance metabolism, impaired excretion, reduced bile formation, and decreased detoxification capacity.
If liver function abnormalities in individuals with "big three positive" (positive for HBsAg, HBeAg, and anti-HBc) are mild, there usually won't be obvious functional impairments; however, severe cases may lead to significant changes in liver function.
1. No
Liver function abnormalities in "big three positive" individuals are typically caused by liver damage resulting from hepatitis B virus infection, leading to structural disruption of the liver. If the damage is mild, the liver's metabolic capacity generally compensates well, so obvious functional abnormalities do not usually occur.
2. Yes
If the liver damage is more severe, it may cause functional abnormalities such as impaired metabolism, excretion problems, reduced bile formation, and decreased detoxification ability. Without timely treatment, this may progress to liver fibrosis, cirrhosis, and in severe cases, even trigger liver cancer.
Patients with "big three positive" and abnormal liver function should follow their doctor's guidance and undergo standardized treatment.
