Why do people get prion diseases?

Mar 29, 2023 Source: Cainiu Health
Dr. Yang Shuwen
Introduction
Prion diseases are generally caused by factors such as genetic predisposition, gene mutations, or prion protein infection. Under a doctor's guidance, treatment may include nutritional support for nerve cells and cellular nourishment to help alleviate symptoms. Additionally, if medical instruments used by healthcare workers are not properly disinfected, patients who come into contact with them may be at risk of developing the disease.

   Prion diseases are generally caused by genetic factors, gene mutations, or prion protein infections.

   1. Genetic Factors

   This disease is usually caused by lesions in the central nervous system and is mostly inherited. For example, if one of the parents has the disease, it may be passed on to the next generation. Currently, there is no effective treatment available; management is based on clinical symptoms with corresponding therapeutic approaches.

   2. Gene Mutation

   The onset of this disease may also result from gene mutations in patients, such as the development of spongiform changes in brain tissue. After onset, it typically leads to dementia, muscle spasms, and muscle weakness. There are usually no specific treatments, but under a doctor's guidance, therapies aimed at nourishing nerve cells and supporting cellular health may help alleviate symptoms.

   3. Prion Protein Infection

   Prion disease is a rare, low-incidence infectious disorder affecting the central nervous system and has certain transmissible properties. It mainly enters the human body through broken skin or mucous membranes. Contact with poultry and wild animals may be a contributing factor.

   In addition, inadequate sterilization of medical instruments used by healthcare workers may pose a risk. If patients come into contact with such contaminated instruments, it could potentially trigger the disease.