Can I keep the baby if I'm pregnant and have "big three positive" (a term referring to positive results for HBsAg, HBeAg, and anti-HBc in hepatitis B testing)?
Apr 10, 2023
Source: Cainiu Health
Dr. Jiang Weimin
Introduction
It is generally acceptable to continue a pregnancy when having "big three positives." "Big three positives" refers to chronic hepatitis B patients or individuals carrying the hepatitis B virus who test positive for three specific markers of the virus. If a woman with "big three positives" becomes pregnant, she can usually follow medical advice and take antiviral medications such as tenofovir alafenamide fumarate tablets to effectively block mother-to-child transmission. The blocking rate typically exceeds 95%. Therefore, in most cases, continuing the pregnancy is feasible.
Hepatitis B "big three positive" patients can usually continue pregnancy under normal circumstances, but must follow medical advice and receive standardized treatment.
"Big three positive" refers to chronic hepatitis B patients or carriers of the hepatitis B virus who test positive for three specific markers. This condition may cause symptoms such as dizziness, fatigue, loss of appetite, dark urine, and in more severe cases, signs like hepatic facies, palmar erythema, spider nevi, and splenomegaly. However, if a woman with "big three positive" status becomes pregnant, she can usually take prescribed antiviral medications—such as tenofovir alafenamide fumarate tablets—as directed by her doctor to effectively block mother-to-child transmission. The transmission blocking rate can exceed 95%. Therefore, pregnancy in "big three positive" patients is generally manageable and can be continued.
After becoming pregnant, women should follow their doctor's instructions for regular follow-up examinations and appropriate drug therapy to manage the condition.
