What factors can cause fetal arrest?

Uterine malformation, neural tube defects, chromosomal abnormality-related genetic disorders, and other factors may lead to fetal arrest. The details are as follows:

1. Uterine Malformation

Abnormal hormone secretion, drug stimulation, congenital inheritance, and other factors may trigger uterine malformation, resulting in uterine dysfunction. This can prevent the normal growth and development of the embryo after implantation in the endometrium, thus leading to fetal arrest. Therefore, prior to pregnancy, individuals should undergo relevant examinations at a qualified medical institution and receive targeted treatment based on the specific cause of uterine malformation.

2. Neural Tube Defects

If the maternal body lacks sufficient folic acid (pteroylglutamic acid) before pregnancy, it may result in poor nutrition of the central nervous system during early gestation, impairing its normal development and causing neural tube defects. If a fetus develops severe neural tube defects that prevent proper cranial development, the aforementioned situation may occur.

3. Chromosomal Abnormality-Related Genetic Disorders

If either parent has chromosomal abnormalities, the resulting embryo may inherit chromosomal disorders after implantation. In such cases, the probability of fetal survival is low, which may consequently lead to fetal arrest.

In addition, placenta previa causing intrauterine hypoxia may also result in fetal arrest. It is recommended to undergo a comprehensive physical examination before pregnancy to rule out potential factors affecting normal fetal development.