Is an endometrial thickness of 1.3 cm with inhomogeneous echogenicity serious?

Whether an endometrial thickness of 1.3 cm with uneven echogenicity is serious depends on the underlying cause. The specific analysis is as follows:

1. Not serious

If the change is due to normal menstrual cycle-related fluctuations in the endometrium, it is considered a physiological phenomenon. Typically, the endometrium will naturally recover after ovulation, so this condition is not serious.

2. Serious

If it is caused by pathological factors—such as excessive estrogen secretion or polycystic ovary syndrome (PCOS) leading to endocrine disorders—it can be more serious. Without treatment, it may affect normal ovulation and even lead to loss of fertility.

For cases caused by pathological factors, treatment under a doctor's guidance with progestin medications is recommended. Commonly used drugs include drospirenone-ethinyl estradiol tablets, progesterone capsules, and dydrogesterone tablets, which help regulate endocrine imbalances.