What does it mean when the quantitative result of hepatitis B DNA is less than 100?
May 10, 2023
Source: Cainiu Health
Dr. Yang Ziqi
Introduction
A quantitative HBV DNA level of less than 100 indicates a low viral load, meaning fewer virus particles per milliliter of blood. This usually suggests a low level of viral replication or that the virus is in a non-replicative state. Due to the low viral load, patients with HBV DNA levels below 100 generally have weak infectivity or are essentially non-infectious.
HBV DNA quantitative level below 100 typically refers to a hepatitis B virus (HBV) DNA test result of less than 100 IU/mL or 100 copies/mL. The analysis is as follows:
An HBV DNA level below 100 indicates a low viral load in each milliliter of blood, meaning fewer virus particles are present. This usually suggests a low level of viral replication or that the virus is in a non-replicative state. Due to the low viral load, patients with HBV DNA levels below 100 generally have weak infectivity or are essentially non-infectious, thereby reducing the risk of transmission to others via blood, sexual contact, mother-to-child transmission, and other routes.
If a patient is currently undergoing treatment and has an HBV DNA level below 100, whether to continue or suspend treatment should be evaluated based on liver function, degree of liver fibrosis, clinical symptoms, and other factors. Some patients with low viral loads and stable conditions may not require antiviral therapy but should undergo regular follow-up monitoring. For patients with hepatitis B complicated by cirrhosis or liver cancer, even if HBV DNA levels are within the normal range, decisions regarding discontinuation or adjustment of treatment must be made according to individual circumstances.
Patients are advised to undergo regular HBV DNA quantitative testing, as well as related examinations such as liver function tests and complete blood counts, to promptly detect any disease changes and implement appropriate treatment measures.
