Is hepatitis B surface antigen and hepatitis B core antibody positivity infectious?

May 10, 2023 Source: Cainiu Health
Dr. Jiang Weimin
Introduction
HBsAg-positive and anti-HBc-positive indicates acute or chronic hepatitis B infection, which is moderately infectious. Hepatitis B is an infectious disease caused by the hepatitis B virus and can be transmitted through body fluids such as blood and semen. When HBsAg and anti-HBc are both positive, viral load is at low to moderate levels, but the individual remains infectious.

Hepatitis B surface antigen positive and core antibody positive (commonly referred to as "positive for item 1 and item 5") indicates acute or chronic hepatitis B infection, which is associated with a certain degree of infectivity. The details are as follows:

Hepatitis B is a contagious disease caused by the hepatitis B virus (HBV), which can be transmitted through bodily fluids such as blood and semen. Once the hepatitis B virus enters human cells and begins to replicate, it leads to high levels of virus in the infected individual and can be passed on to others through close contact. The higher the hepatitis B viral DNA level, the more active the viral replication and the greater the infectivity. At this stage, the hepatitis B surface antigen and core antibody are positive, while the other three markers are negative. Although the viral load may be at a moderate or low level, the individual remains infectious.

Patients with hepatitis B should receive treatment under the guidance of a physician, maintain healthy lifestyle and dietary habits, engage in appropriate physical exercise, enhance immune function, and prevent worsening of symptoms.