What are the precautions for intravenous infusion of butylphthalide?

May 11, 2023 Source: Cainiu Health
Dr. Yang Shuwen
Introduction
Precautions for intravenous infusion of butylphthalide generally include contraindication in patients with allergies, and cautious use in those with bradycardia or sick sinus syndrome. Additionally, caution should also be exercised when administering to patients with impaired liver function or a significant tendency toward bleeding. If butylphthalide intravenous infusion is required, patients are advised to use the medication under the guidance of a physician and avoid self-administration.

 Precautions for intravenous infusion of butylphthalide generally include contraindication in patients with allergies, cautious use in those with bradycardia, and cautious use in patients with sick sinus syndrome. The specific analysis is as follows:

1. Contraindicated in allergic individuals

The main component of butylphthalide is dl-3-n-butylphthalide, which can be used to treat mild to moderate acute ischemic stroke. If a patient is allergic to any component of butylphthalide, the drug should be avoided to prevent allergic reactions such as rash and itching.

2. Use with caution in patients with bradycardia

Butylphthalide can be used during the acute phase of cerebral infarction and is effective only within 48 hours after onset. Patients presenting with bradycardia are advised not to use butylphthalide.

3. Use with caution in patients with sick sinus syndrome

Butylphthalide is an anti-ischemic agent. During treatment, caution should be exercised when administering this drug to patients diagnosed with sick sinus syndrome.

In addition, caution should also be exercised in patients with impaired liver function or a significant tendency toward bleeding. If intravenous butylphthalide therapy is required, patients should use the medication under the guidance of a physician and avoid self-administration.


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