What are the strong antihypertensive drugs?

Strong antihypertensive drugs refer to medications with relatively effective blood pressure-lowering effects, generally including angiotensin II receptor blockers, beta-blockers, and diuretics. Specific details are as follows:

1. Angiotensin II Receptor Blockers

This category typically includes medications such as olmesartan medoxomil tablets, telmisartan tablets, and irbesartan hydrochlorothiazide tablets. These drugs primarily work by selectively blocking angiotensin II receptors, thereby preventing angiotensin II from exerting its effects. Additionally, angiotensin II receptor blockers tend to cause less kidney damage.

2. Beta-Blockers

Beta-blockers mainly function by blocking β1 receptors in the heart and juxtaglomerular cells, reducing myocardial contractility, decreasing cardiac output, and suppressing the activity of excitatory neurons. Common examples include metoprolol tablets, bisoprolol fumarate tablets, and atenolol tablets.

3. Diuretics

These drugs lower blood pressure primarily by increasing sodium excretion, reducing extracellular fluid volume, and decreasing peripheral vascular resistance. Typical examples include torasemide tablets, hydrochlorothiazide tablets, and furosemide tablets.

In addition, calcium channel blockers and angiotensin-converting enzyme (ACE) inhibitors can also achieve good blood pressure-lowering effects.