What causes soreness and swelling in the lower leg after intravenous infusion?

May 13, 2023 Source: Cainiu Health
Dr. Lin Yunfei
Introduction
Leg soreness and swelling after intravenous infusion may result from physiological factors such as prolonged sitting, or pathological causes including drug irritation and muscle strain. It is recommended to choose appropriate treatment based on the specific condition. In addition to the above-mentioned factors, it could also be related to piriformis syndrome, lumbar disc herniation, or deep vein thrombosis in the lower limbs. Adequate bed rest and minimizing unnecessary physical activity are advised.

Acidic swelling in the lower leg after intravenous infusion may be caused by physiological factors such as prolonged sitting, or triggered by pathological factors such as drug irritation or muscle strain. It is recommended to choose appropriate treatment measures based on specific circumstances. Detailed analysis is as follows:

I. Physiological Factors

If a fixed posture is maintained during infusion, leading to leg compression and impaired blood circulation, discomfort such as soreness and swelling may occur after completion of the infusion. This usually resolves with appropriate movement and does not require special treatment.

II. Pathological Factors

1. Drug Irritation
Infusing too quickly or being allergic to certain drug components can cause adverse stimulation, resulting in numbness, discomfort, leg pain, weakness, and similar symptoms. Generally, symptoms resolve spontaneously as the drug is metabolized in the body. However, if adverse reactions are severe, prompt medical attention is required.

2. Muscle Strain
Prolonged standing, running, or similar activities may stretch leg muscles, causing varying degrees of injury, thus leading to symptoms such as lower leg soreness, swelling, and pain. This condition is unrelated to intravenous infusion. For severe soreness, medications such as diclofenac sodium sustained-release capsules, nimesulide granules, or loxoprofen sodium tablets may be taken under medical guidance, along with leg massage.

Besides the above factors, conditions such as piriformis syndrome, lumbar disc herniation, or deep vein thrombosis in the lower limbs may also be involved. Adequate bed rest and minimizing unnecessary physical activity are advised.

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