Can I drink alcohol at noon if I took cephalosporin in the morning?

Under normal circumstances, you should not drink alcohol at noon after taking cephalosporin antibiotics in the morning, to avoid triggering a disulfiram-like reaction. The detailed explanation is as follows:

Normally, it takes the human body 24 to 48 hours to metabolize cephalosporin drugs. If you take cephalosporins in the morning, the drug may not have been completely eliminated from your body by noon. Drinking alcohol at this time could lead to the accumulation of acetaldehyde, which interacts with the residual cephalosporin and causes a disulfiram-like reaction. Symptoms may include dizziness, headache, nausea, vomiting, low blood pressure, facial flushing, and rapid breathing. In severe cases, it may even result in coma, shock, or death. Therefore, it is recommended to avoid alcohol consumption during treatment with cephalosporins and only resume drinking after completing the full course of medication and stopping the drug. If alcohol consumption is absolutely necessary, it is advised to wait at least 48 hours after the last dose, and even then, alcohol should be consumed in moderation to prevent excessive intake.

During treatment with cephalosporin antibiotics, you should strictly follow your doctor’s instructions and medication guidelines to avoid unnecessary risks and side effects. If you experience any discomfort or adverse symptoms while taking the medication, seek medical attention promptly.