Does Detong Pian (pain-relieving tablet) harm the kidneys?

Analgesic tablets can cause kidney damage. Taking analgesic tablets may lead to gastric mucosal injury, kidney damage, liver damage, and other issues. The specific analysis is as follows:

1. Gastric Mucosal Injury

Analgesic tablets irritate the gastric mucosa. The aminopyrine component in analgesic tablets inhibits the synthesis and release of prostaglandins in inflamed tissues. Without protection from prostaglandins, the gastric mucosa becomes vulnerable to damage from gastric acid. Long-term use of analgesic tablets may result in gastric mucosal ulcers, erosion, and similar conditions.

2. Kidney Damage

Components such as phenacetin in analgesic tablets must be excreted through the kidneys. Prolonged use of these tablets can lead to kidney damage. In severe cases, this may result in renal papillary necrosis or uremia, and could even induce cancers of the renal pelvis and bladder.

3. Liver Damage

Analgesic tablets are metabolized by the liver. Long-term use can cause liver damage, leading to symptoms such as abdominal pain, nausea, and darkened urine.

In addition to the above, long-term use of analgesic tablets may also lead to drug dependence and neutropenia. If the medication is used for more than one week, blood tests should be performed regularly to monitor hematological parameters and detect any abnormalities. Patients should take analgesic tablets only under the guidance of a qualified physician, using an appropriate dosage. Excessive dosage or prolonged use can pose serious health risks. If any adverse symptoms occur during treatment, patients should seek medical attention promptly and receive appropriate care under a doctor's supervision.