Is a glomerular filtration rate of 133 ml/min severe?

May 16, 2023 Source: Cainiu Health
Dr. Zhao Xinju
Introduction
A glomerular filtration rate (GFR) of 133 ml/min may be a normal physiological phenomenon. If the individual is pregnant, the body increases renal blood flow to accommodate fetal growth and development, which can lead to an elevated GFR—this is considered a normal physiological change. If the individual is not pregnant, conditions such as acromegaly or gigantism should be considered, although the degree of elevation in this value is not particularly severe.

Generally, the unit for glomerular filtration rate (GFR) is ml/min. A GFR of 133 ml/min may represent a normal physiological phenomenon or an abnormal condition caused by disease, but it does not fall into a particularly severe category. The specific analysis is as follows:

GFR is used to assess whether an individual's kidney function is normal. The normal range for adult GFR is between 90 and 120 ml/min. A measured value of 133 ml/min indicates that it is above the normal range. If the person being tested is pregnant, this increase can be a normal physiological occurrence. During pregnancy, the body increases blood volume and cardiac output to support fetal growth and development, which also increases renal blood flow and consequently elevates GFR. In such cases, no special intervention is usually required. However, if the individual is not pregnant, a GFR above the normal range may be associated with conditions such as acromegaly or gigantism. These disorders involve excessive secretion of growth hormone, which can increase GFR. Nevertheless, a value of 133 ml/min does not indicate a particularly severe elevation. It is recommended that patients undergo further examinations to determine the exact underlying cause and receive targeted treatment accordingly.

During treatment, adjusting diet alone is insufficient, as dietary changes alone cannot fully correct this parameter.