What does elevated B-type natriuretic peptide indicate, and how high is considered dangerous?
May 16, 2023
Source: Cainiu Health
Dr. Zhao Xinju
Introduction
Elevated B-type natriuretic peptide (BNP) is one of the indicators of cardiac function. However, test results may vary depending on the hospital's testing methods and the patient's age. For individuals under 50 years old, a BNP level exceeding 500 pg/mL suggests heart failure. For middle-aged and elderly patients between 50 and 70 years old, a BNP level above 900 pg/mL indicates heart failure.
Under normal circumstances, elevated B-type natriuretic peptide (BNP) levels suggest the possibility of heart failure and is one of the indicators of cardiac function. Generally, a level exceeding 300 pg/mL indicates a certain degree of risk. However, reference values may vary depending on the testing methods used by different hospitals and the patient's age.
If BNP levels are below 300 pg/mL, heart failure and related conditions can usually be ruled out. For patients under 50 years old, BNP levels above 500 pg/mL indicate a certain risk and suggest possible heart failure. In middle-aged and elderly individuals aged 50 to 70 years, a BNP level higher than 900 pg/mL can be used as an indicator for diagnosing heart failure. Higher BNP levels generally correlate with greater severity of heart failure; however, a comprehensive assessment should also include the patient’s medical history, clinical symptoms, and other test results.
In most patients with heart failure, abnormal test results appear early, along with symptoms of underlying diseases and causes of heart failure. Once the cause is identified, timely management of heart failure is essential to prevent death due to heart failure. Treatment primarily includes medication and measures to reduce both preload and afterload on the heart.
