What is the normal value for total protein to creatinine ratio?
May 16, 2023
Source: Cainiu Health
Dr. Zhao Xinju
Introduction
The total protein-to-creatinine ratio is an effective method for early detection of kidney damage. Under normal circumstances, the urinary protein-to-creatinine ratio ranges from 0.10 to 0.20, and the total urine protein is less than 150 mg/24h; therefore, the total protein-to-creatinine ratio is generally below 300 mg/g. If the ratio is elevated, prompt medical evaluation is necessary to determine the underlying cause and initiate appropriate treatment.
Under normal circumstances, the total protein-to-creatinine ratio is generally less than 300 mg/g. The specific analysis is as follows:
The total protein-to-creatinine ratio is an effective method for early detection of kidney damage. When certain diseases such as diabetes or hypertension are present, they can damage vascular endothelial cell membranes, increasing permeability of systemic microvessels. Due to loss of negative charges in the glomerular basement membrane, injury may occur, allowing small-molecular-weight proteins to more easily pass through the glomerular filtration membrane into the urine. These proteins are often not detectable by routine urinalysis and thus the protein-to-creatinine ratio may be used instead to assess early kidney damage. Under normal conditions, the urinary protein-to-creatinine ratio ranges from 0.10 to 0.20, and total urinary protein is less than 150 mg/24h; therefore, the total protein-to-creatinine ratio is generally below 300 mg/g.
If test results show an elevated ratio, prompt medical evaluation at a hospital is necessary to determine the underlying cause and initiate appropriate treatment. In daily life, it is important to maintain a light diet and avoid foods high in protein.
