What are the side effects of coagulation injections?

May 16, 2023 Source: Cainiu Health
Dr. Zhang Heyang
Introduction
Coagulation injections are medications that promote blood clotting, but their use may interfere with the body's anticoagulation mechanisms and increase the risk of bleeding. Additionally, heparin, a component of coagulation injections, can reduce the binding between platelets and clotting factors, leading to thrombocytopenia, and also inhibit collagen synthesis required for bone metabolism, potentially causing osteoporosis. You should immediately inform your doctor if you experience any discomfort.

Generally, coagulation injections may have side effects such as bleeding, thrombocytopenia, and osteoporosis. The specific analysis is as follows:

1. Bleeding

Coagulation injections are medications that promote blood clotting. Their mechanism of action involves activating and aggregating clotting factors, thereby enhancing the blood's ability to coagulate. The use of coagulation injections interferes with the body's natural anticoagulant mechanisms, making blood more prone to clotting and consequently increasing the risk of bleeding.

2. Thrombocytopenia

The main component of coagulation injections is heparin. Heparin binds to antithrombin III, an enzyme inhibitor on the platelet surface, forming a complex that reduces the degree of binding between platelets and clotting factors.

3. Osteoporosis

Coagulation injections primarily exert their anticoagulant effect by inhibiting the synthesis of vitamin K-dependent clotting factors. However, reduced vitamin K levels also suppress the synthesis of collagen required in bone metabolism, potentially leading to osteoporosis.

In addition to the above, other side effects of coagulation injections may include allergic reactions, local redness and swelling, local pain, and fever. If you are currently using coagulation injections and experience any discomfort, you should immediately inform your doctor.