What does a positive dual antibody test mean?

May 16, 2023 Source: Cainiu Health
Dr. Liu Aihua
Introduction
A positive result in the dual antibody test may indicate an increased risk of autoimmune diseases, but it does not necessarily mean that a disease is present. Clinical symptoms and signs must be considered for a comprehensive evaluation. Patients are advised to consult a physician for further assessments, including tests such as immunoglobulin levels, ultrasound, biopsy, and other relevant examinations. Treatment should be conducted under medical supervision. In summary, the interpretation of dual antibody test results and subsequent management should be carried out under the guidance of a physician.

Generally, a positive result in the "double antibody" test indicates the presence of antinuclear antibodies (ANA) and anti-double-stranded DNA (anti-dsDNA) antibodies in the body, which may suggest an increased risk of autoimmune diseases. The specific analysis is as follows:

A positive result in the double antibody test does not necessarily confirm the presence of a disease. Infections, drug reactions, or cancers can also lead to positive results. Therefore, a positive finding must be evaluated in conjunction with the patient's clinical symptoms, physical signs, and other laboratory test results to determine the likelihood of an autoimmune disorder. If the double antibody test is positive, patients are advised to consult a physician for more detailed information and guidance. The doctor may recommend further tests and evaluations, such as immunoglobulin levels, complement C3, and other laboratory indicators. In some cases, additional investigations or treatments—such as ultrasound, biopsy, or immunosuppressive therapy—may be recommended.

In summary, a positive double antibody test may indicate a potential risk of autoimmune diseases and should be assessed together with the patient’s clinical symptoms, physical findings, and other laboratory results. It is recommended that testing and treatment be conducted under the guidance of a healthcare professional.