What are the toxic symptoms in muscles due to overdose of local anesthetics?

May 16, 2023 Source: Cainiu Health
Dr. Yang Shuwen
Introduction
When local anesthetics are overdosed, muscles may develop spasms and edema, and dizziness may also occur. Excessive local anesthetic entering the bloodstream can damage nervous tissues, leading to muscle spasms. Injecting high concentrations of anesthetic into the skin and subcutaneous tissue can cause temporary edema. Moreover, local anesthetics may cause blood pressure fluctuations, leaving the brain in a state of ischemia and hypoxia, resulting in dizziness and headaches.

Under normal circumstances, an overdose of local anesthetic may cause muscle spasms, edema, and dizziness. The specific analysis is as follows:

1. Muscle spasms

When excessive local anesthetic enters the bloodstream, it may lead to a sudden increase in blood concentration of the anesthetic, causing damage to nervous tissue and resulting in muscle spasms.

2. Edema

When high concentrations of anesthetic are injected into the skin or subcutaneous tissue, temporary edema may occur if the body cannot fully absorb the drug.

3. Dizziness

After administration of local anesthetic, an allergic reaction may cause fluctuations in blood pressure. When blood pressure drops too low, the brain may become ischemic and hypoxic, leading to symptoms such as dizziness and headache.

In addition to the above symptoms, difficulty breathing and rapid heartbeat may also occur. If any of these symptoms appear, timely medical treatment should be sought to facilitate recovery. In daily practice, local anesthetics should not be self-administered to avoid improper dosage control; instead, dosage must be managed by a qualified physician.