What causes a low fever to turn into a high fever?

Low fever refers to mild fever, while high fever refers to elevated fever. A transition from low to high fever may be caused by bacterial infection, pneumonia, systemic lupus erythematosus, and other conditions. Specific causes are analyzed as follows:

1. Bacterial cold (bacterial infection)

Prolonged physical exhaustion may cause heat accumulation in the body, leading to symptoms of low-grade fever. At this time, immunity is relatively low. Without proper protection, patients may become infected with bacteria, resulting in bacterial infection that affects the body's temperature regulation center and leads to high fever. Under medical guidance, patients can take medications such as azithromycin tablets or amoxicillin capsules for treatment.

2. Pneumonia

If a patient lives in an area with poor air quality, harmful substances may enter the body and trigger pneumonia. This inflammatory condition releases cytokines and other inflammatory factors, potentially causing a progression from low-grade to high fever. Under medical supervision, patients may use medications such as acyclovir capsules or cefadroxil and trimethoprim tablets for treatment.

3. Systemic lupus erythematosus (SLE)

If a patient experiences abnormal hormone levels recently, it may trigger systemic lupus erythematosus, generating large amounts of endogenous pyrogens and resulting in high fever. Under a doctor’s guidance, patients can use hydroxychloroquine sulfate tablets or mycophenolate mofetil for injection as part of treatment.

In addition to the above causes, high fever may also result from meningitis, rheumatoid arthritis, influenza, dengue fever, and other conditions. If high fever occurs, prompt medical attention is recommended to avoid delayed diagnosis and potentially serious complications.