What are the side effects of long-term use of Rhodiola?

Long-term use of Rhodiola may commonly lead to side effects such as gastrointestinal reactions, allergic reactions, and drug interactions. A detailed analysis is as follows:

1. Gastrointestinal reactions

The components in Rhodiola may irritate the gastrointestinal tract, causing symptoms such as nausea, vomiting, and diarrhea.

2. Allergic reactions

Rhodiola contains certain active ingredients, such as phenylethanoids and flavonoids, which may trigger allergic reactions like rashes and urticaria. Therefore, individuals with allergic predispositions should avoid taking Rhodiola or use it only under medical supervision.

3. Drug interactions

Rhodiola contains a variety of active compounds that may affect the metabolism and absorption of other medications, including anticoagulants and antihypertensives, such as enteric-coated aspirin tablets and sustained-release nifedipine tablets. Patients taking Rhodiola long-term should consult a physician or pharmacist to avoid adverse drug interactions.

In addition to the above side effects, symptoms such as headache, insomnia, and palpitations may also occur. If side effects are severe or persist for an extended period, prompt medical attention is recommended.