What causes a low percentage of segmented neutrophils in the granulocytic series on a blood smear?

In general, a low neutrophil segmented nucleus count in blood smears may be associated with factors such as infections, aplastic anemia, and autoimmune diseases. The specific analysis is as follows:

1. Infections

Common infections include bacterial and viral infections, such as typhoid fever, influenza, and viral hepatitis. These conditions can lead to a reduced neutrophil segmented nucleus count in blood smears. Under a doctor's guidance, medications such as ofloxacin tablets, roxithromycin capsules, or ribavirin granules may be prescribed.

2. Aplastic Anemia

In cases of aplastic anemia, bone marrow failure impairs the normal production of neutrophil segmented cells, resulting in decreased counts. For severe anemia accompanied by infection, glucocorticoids such as prednisone tablets or dexamethasone tablets may be used under medical supervision to improve symptoms.

3. Autoimmune Diseases

Conditions like systemic lupus erythematosus may also cause a low neutrophil segmented nucleus count. Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen sustained-release capsules or aspirin capsules, may be selected under a doctor’s guidance.

In addition, exposure to X-rays, gamma rays, or radioactive isotopes may also lead to a reduced neutrophil segmented nucleus count. Patients are advised to seek timely medical evaluation at a hospital to determine the underlying cause before initiating treatment.