What does the hematopoietic microenvironment include?
May 26, 2023
Source: Cainiu Health
Dr. Zhang Heyang
Introduction
Under normal circumstances, the hematopoietic microenvironment includes the microvascular system, peripheral nerves, reticular cells, etc. In addition to these components, other elements such as bone marrow stroma and cytokines secreted by stromal cells also play important roles. Hematopoietic cells in the bone marrow grow and develop supported by non-hematopoietic tissues. In daily life, appropriate physical exercise is recommended, such as jumping rope, running, and cycling.
Under normal circumstances, the hematopoietic microenvironment includes the microvascular system, peripheral nerves, reticular cells, and others. The specific details are as follows:
1. Microvascular System
The microvascular system refers to the network of tiny blood vessels within the cardiovascular system. Microvessels are the smallest vessels connecting arterioles and venules. These cells overlap and interconnect with each other, visible only under a microscope.
2. Peripheral Nerves
Peripheral nerves are the distal terminal portions of the peripheral nervous system, including sensory nerves, motor nerves, and autonomic nerves. Peripheral nerves are components of the hematopoietic microenvironment.
3. Reticular Cells
Reticular cells participate in the maintenance and self-renewal of hematopoietic stem cells and are part of the hematopoietic microenvironment.
In addition to the above, other factors such as bone marrow stroma and cytokines secreted by stromal cells also contribute to the hematopoietic microenvironment. Hematopoietic cells in the bone marrow develop and mature on a non-hematopoietic tissue matrix. In daily life, appropriate physical exercise such as rope skipping, running, and cycling is recommended.
