Can calamine lotion be applied for G6PD deficiency (favism)?

May 27, 2023 Source: Cainiu Health
Dr. Liu Wan
Introduction
Calamine refers to calamine lotion. Patients with favism can usually apply calamine lotion. Favism is a group of inherited hemolytic disorders caused by mutations in the glucose-6-phosphate dehydrogenase (G6PD) gene, which may lead to symptoms such as dizziness, fatigue, and pallor. Calamine lotion is a commonly used topical preparation in dermatology, primarily containing calamine and zinc oxide, and is non-irritating to human skin.

Liquid calamine refers to calamine lotion. Patients with favism (G6PD deficiency) can usually apply calamine lotion. The details are as follows:

Favism is a group of inherited hemolytic disorders caused by mutations in the glucose-6-phosphate dehydrogenase (G6PD) gene, which may lead to symptoms such as dizziness, fatigue, and pallor. Calamine lotion is a commonly used topical preparation in dermatology and generally contains ingredients such as calamine, zinc oxide, and glycerin, which are non-irritating to the skin. Its main effects are astringent and anti-itching, primarily used to treat skin itching caused by various conditions such as acute and chronic urticaria, acute eczema, and papular urticaria. It helps reduce skin edema and relieve itching. Therefore, calamine lotion does not adversely affect the occurrence or progression of favism.

Medications should be used under the guidance of a physician; self-medication should be avoided to prevent potential harm to the body. In daily life, attention should be paid to dietary adjustments, avoiding spicy and greasy foods. Adequate rest is important—avoid excessive fatigue and prolonged熬夜 (staying up late). Engaging in appropriate physical exercise can help enhance immunity.