What does it mean when the absolute value of neutrophil segmented cells is low, and what should be done?

Under normal circumstances, a low absolute value of neutrophil segmented granulocytes may be related to physiological factors, or it could be associated with pathological conditions such as typhoid fever and megaloblastic anemia. Different causes require different treatment approaches. The specific details are as follows:

I. Physiological Factors

Neutrophil segmented granulocytes are a type of neutrophil within white blood cells. Normally, the reference range for neutrophil segmented granulocytes is 2–7 × 10^9/L, and values below 2 × 10^9/L are considered low. Prolonged exposure to X-rays, gamma rays, radioactive isotopes, or similar substances may lead to a decreased absolute count of neutrophil segmented granulocytes. In such cases, individuals should immediately leave these environments, ensure adequate rest, and maintain a light diet. Generally, there will not be significant adverse effects.

II. Pathological Factors

1. Typhoid Fever

Typhoid fever is caused by infection with Salmonella typhi bacteria. Patients typically present with persistent high fever, rose-colored skin rashes, hepatosplenomegaly (enlarged liver and spleen), and may also exhibit the aforementioned condition. Patients should adjust their dietary habits, consuming appropriate amounts of protein- and vitamin-rich foods. Additionally, medications such as levofloxacin tablets or ciprofloxacin hydrochloride capsules may be taken as directed by a physician.

2. Megaloblastic Anemia

In megaloblastic anemia, hematopoietic stem cell function in the bone marrow may decline, leading to a reduced absolute count of neutrophil segmented granulocytes. This condition is often accompanied by decreased platelet and red blood cell counts. Patients may experience symptoms such as waxy yellow skin and loss of appetite. Treatment may include taking folic acid tablets or compound vitamin B tablets as prescribed by a doctor.

Besides the above, this condition may also be associated with rickettsial infections, rheumatoid arthritis, systemic lupus erythematosus, sepsis, leukemia, and other diseases. It is recommended that patients seek timely medical care at a hospital to prevent adverse impacts on health.