What does it mean if B lymphocyte CD3-CD19+ is low, and what should be done?

May 30, 2023 Source: Cainiu Health
Dr. Zhang Heyang
Introduction
In general, a low level of CD3-CD19+ lymphocytes may be caused by physiological factors or pathological conditions such as pneumonia or rheumatoid arthritis, and treatment should be tailored according to the specific condition. It may also result from other causes, such as long-term use of glucocorticoids or acquired immunodeficiency syndrome (AIDS).

Under normal circumstances, a low level of B lymphocytes CD3-CD19+ may be caused by physiological factors or pathological conditions such as pneumonia or rheumatoid arthritis. Appropriate treatment should be based on the specific cause. Details are as follows:

I. Physiological Factors

If patients have habits such as staying up late or suffer from malnutrition, their immune function may decrease. In such cases, B lymphocytes CD3-CD19+ levels may temporarily drop. This is considered normal and does not require special treatment. Levels typically return to normal after adequate rest and dietary adjustments.

II. Pathological Factors

1. Pneumonia

Pneumonia is usually caused by bacterial infection, which can affect the immune system and lead to reduced levels of B lymphocytes CD3-CD19+. Patients often present with symptoms such as fever and cough. It is recommended to seek timely evaluation at a reputable hospital and follow medical advice to take medications such as amoxicillin dispersible tablets or cefaclor dispersible tablets.

2. Rheumatoid Arthritis

This is an autoimmune disorder characterized by immune system dysfunction. Common manifestations include gastrointestinal bleeding, purpura, and inflammatory polyarthritis affecting small joints in the hands and feet. Laboratory tests often reveal decreased levels of B lymphocytes CD3-CD19+. Patients should follow medical guidance to use medications such as ibuprofen sustained-release capsules or acetaminophen tablets for treatment.

In addition to the above causes, other possible reasons include long-term use of glucocorticoids, acquired immunodeficiency syndrome (AIDS), and congenital X-linked agammaglobulinemia. Patients are advised to seek prompt medical attention at a qualified hospital.