High estrogen during menopause

Menopause, also known as perimenopausal syndrome, may involve elevated estrogen levels due to either physiological or pathological factors, such as viral hepatitis or pituitary tumors. The specific analysis is as follows:

I. Physiological Factors

Perimenopausal syndrome generally refers to a condition in which ovarian follicles no longer respond to estrogen stimulation and thus fail to develop properly. As a result, the endometrium no longer thickens, and the body's utilization of estrogen decreases, leading to relatively elevated estrogen levels. This condition can be alleviated through regular physical exercise and maintaining endocrine stability.

II. Pathological Factors

1. Viral Hepatitis

Viral hepatitis may be caused by infections such as hepatitis B virus or hepatitis A virus. These infections damage liver cells, impairing the liver’s ability to normally regulate estrogen activity, thereby causing the aforementioned symptoms. Treatment may include medications such as sofosbuvir tablets or entecavir tablets, taken under medical supervision.

2. Pituitary Tumor

Pituitary tumors may be triggered by genetic factors, gene mutations, or hypothalamic hormone dysregulation. Abnormal overactivity in the pituitary gland can lead to excessive hormone secretion, resulting in elevated estrogen levels. This condition can be treated at a qualified medical facility via transnasal transsphenoidal microscopic surgery.

In addition, elevated estrogen levels during perimenopausal syndrome may also be caused by obesity, liver cirrhosis, ovarian cancer, and other conditions. It is recommended to maintain a light and balanced diet during treatment.