What does it mean to be HPV16 positive with a negative HPV DNA test?
Jun 01, 2023
Source: Cainiu Health
Dr. Lv Aiming
Introduction
HPV16 positive, but HPV DNA test negative, usually indicates the presence of human papillomavirus in the body without cancerous changes. A positive HPV16 result generally means the patient is infected with human papillomavirus type 16. At this point, an HPV DNA test is typically performed for diagnostic purposes; if the result is negative, cervical cancer can usually be ruled out.
HPV16 positive with negative HPV DNA test generally indicates the presence of human papillomavirus in the patient's body, but without malignant transformation. The detailed analysis is as follows:
An HPV16-positive result usually means the patient is infected with human papillomavirus type 16, which may lead to cervical precancerous lesions or cervical cancer. At this point, an HPV DNA test is commonly performed for disease diagnosis. If the result is negative, cervical cancer or precancerous cervical lesions can typically be ruled out. Patients at this stage often experience symptoms such as vulvar itching, increased vaginal discharge, and contact bleeding. Treatment is usually recommended under a doctor's guidance using medications such as Baofukang suppositories or recombinant human interferon α2b gel.
Patients are advised to actively cooperate with their doctors during treatment. Adequate rest should be taken, good sleep habits should be maintained, and staying up late or overexertion should be avoided. Emotional stability is important—excessive anxiety and stress should be minimized to prevent interference with recovery. Additionally, sexual activity should be avoided during treatment to prevent cross-infection.
