A 40-year-old woman experiences knee pain and cannot stand up after squatting.

Knee pain in a 40-year-old woman that makes it difficult to squat or stand up may be caused by calcium deficiency, synovitis, meniscus injury, fat pad inflammation, patellar tendinitis, and other conditions. Treatment should be based on the specific cause. Detailed analysis is as follows:

1. Calcium Deficiency

If long-term picky eating leads to insufficient calcium levels in the body, it may result in inadequate bone formation or bone deterioration, causing knee pain. In severe cases, mobility may also be affected. Patients can follow medical advice to take medications such as calcium gluconate oral solution or calcium carbonate D3 chewable tablets.

2. Synovitis

If trauma occurs or the synovial tissue is invaded over time by pathogens such as bacteria, joint pain may develop. Under a doctor's guidance, patients may take medications like roxithromycin capsules or diclofenac sodium sustained-release tablets.

3. Meniscus Injury

If an injury occurs during exercise leading to damage of the meniscus, significant pain may arise and normal movement may be impaired. Initially, cold compresses can help alleviate symptoms. In severe cases, surgical repair may be required.

4. Fat Pad Inflammation (Hoffa’s Disease)

Fat pad inflammation is primarily caused by degenerative changes in the knee joint, resulting in localized aseptic inflammation, which can lead to knee pain and difficulty squatting or standing up. Under medical supervision, patients may use medications such as ibuprofen tablets or loxoprofen sodium tablets for relief.

5. Patellar Tendinitis

If patellar tendinitis develops, aseptic inflammation in the patellar tendon at the front of the knee joint may occur, potentially causing pain when squatting or standing. Patients may follow medical advice to take medications such as aspirin capsules, tongluo kaibi tablets, or huoxue zhitong capsules.

In addition, conditions such as rheumatoid arthritis, chondromalacia patellae, or osteoarthritis could also be responsible. In summary, if a patient experiences severe knee pain with difficulty squatting or standing, prompt medical evaluation is essential to prevent worsening of the condition.