Are total bile acids a marker of liver function or kidney function?

Total bile acids are usually a test parameter in liver function assessments, primarily used to evaluate the health of the hepatobiliary system. The specific analysis is as follows:

Total bile acids are metabolic products of bile acid synthesized by the liver and excreted into the intestine via bile, where they aid in the digestion and absorption of fats. Therefore, total bile acids serve as one of the indicators in liver function tests, and changes in their levels can help healthcare providers assess the status of the hepatobiliary system. Under normal conditions, the liver maintains a balance of total bile acids. However, if the liver is damaged or diseased, the level of total bile acids may rise. Thus, when liver function tests show abnormally elevated total bile acid levels, this may indicate possible conditions such as viral hepatitis, fatty liver, alcoholic liver disease, liver fibrosis, cholecystitis, or cirrhosis. Additionally, total bile acid levels can be used in liver function testing for pregnant women to help monitor liver changes during pregnancy.

In summary, total bile acids are an indicator of liver function, not kidney function. If patients have concerns regarding their total bile acid levels, they should consult a qualified physician and undergo appropriate diagnosis and treatment.