What is bilateral periventricular leukomalacia, and what should be done about it?

Jun 05, 2023 Source: Cainiu Health
Dr. Yang Jun
Introduction
Bilateral periventricular leukomalacia may be caused by factors such as hypertension, hyperlipidemia, and diabetes, and requires medication based on individual conditions. Long-term hypertension can lead to cerebral arteriosclerosis, resulting in chronic ischemia of the white matter and glial proliferation. The main clinical features include cognitive impairment, which can be treated with medications such as nifedipine sustained-release tablets and losartan potassium tablets under medical guidance.

Bilateral periventricular leukomalacia may be caused by factors such as hypertension, hyperlipidemia, and diabetes. Treatment should be based on specific conditions with appropriate medication. Details are as follows:

1. Hypertension

Long-term hypertension can lead to cerebral arteriosclerosis, resulting in chronic ischemia of white matter, demyelination, and glial proliferation. Main clinical features include cognitive impairment and dementia. Medications such as nifedipine controlled-release tablets or losartan potassium tablets may be taken according to medical advice.

2. Hyperlipidemia

Prolonged hyperlipidemia causes excessive lipid components in the blood to deposit in blood vessels, leading to multiple atherosclerotic lesions and softening of bilateral periventricular white matter. Treatment may include medications such as lovastatin capsules or atorvastatin calcium tablets under a doctor's guidance.

3. Diabetes

Insulin secretion or utilization disorders caused by various factors may affect the brain, leading to symptoms such as dizziness and limb weakness. Medications such as sitagliptin phosphate tablets or empagliflozin tablets may be used under medical supervision.

In addition to the above causes, bilateral periventricular leukomalacia could also result from insufficient cerebral blood supply, cerebral hemorrhage, or cerebral infarction. Adequate rest and avoidance of excessive fatigue are recommended. Patients should seek timely medical attention when experiencing discomfort and receive standardized treatment under professional guidance to promote recovery.